Buffalo’s Original Pizzeria Since 1927

We are Buffalo’s original pizzeria and a true local institution, serving iconic Buffalo-style pizza since 1927. Craving a taste of the city’s soul? Santora’s delivers cheesy, pepperoni-packed perfection with hometown pride. Serving Cheektowaga, Elma, Lancaster, Depew, and West Seneca.

A person holding a slice of pepperoni and black olive pizza with melted cheese dripping. There is a whole pizza on the table with the same toppings, and a white plate on a red-checked tablecloth.
A digital illustration of red blood cells scattered across a black background.
Red abstract geometric shape with curved and pointed edges.

Your Pizza Party

Come celebrate Buffalo’s pizza heritage with us

Hearty portions and bold flavors define us—a true taste of Buffalo’s pizza heritage, crafted from family recipes since 1927.  

Heart-shaped pizza topped with pepperoni slices and black olives, sitting on a red and white checkered paper.

Our menu centers on thick, airy, circular pizzas with a crisp crust, sweet tomato sauce, and generous Sorrento mozzarella. The signature touch is hand-cut, cup-and-char pepperoni finished with savory Romano “fufu dust.” Pizzas come in medium, large, or party sizes.  

Toppings include sausage, mushrooms, onions, and specialties like the Stinger Bold (chicken, hot sauce, mozzarella) or White Pizza (chopped tomatoes, onions, mozzarella, garlic).  

A bowl of boneless chicken wings covered in barbecue sauce placed on a red and white checkered paper tablecloth.

Beyond pizza, enjoy jumbo baked wings in sauces from mild to hot, served with bleu cheese. Our subs on fresh-baked rolls feature favorites like Philly Steak or Chicken Finger. Calzones are loaded with sauce, mozzarella, and your choice of toppings, while crisp Antipasto salads round out lighter options.  

Sides include mozzarella sticks, pizza logs, and cheesy garlic bread. Combo deals like pizza and wings are perfect for sharing.

A table with a variety of foods including two large pepperoni pizzas, French fries, a plate of chicken wings, a bowl of barbecue ribs, salt and pepper shakers, and bottles of condiments on a red checkered tablecloth.

Pull Up A Chair

Your pizza party starts here!

Our party servings are perfect for feeding 12 to 40 hungry family members. Each recommended serving delivers two generous slices of pizza and three juicy wings per person. Need more? Just let us know. Order weeks ahead or give us just one hour’s notice and we’ll be there to welcome you. There’s always room at Grandma’s table!

About Us

On the Niagara frontier, it’s Santora’s!

Family owned and operated for over 99 years. Buffalo’s oldest pizzeria and originator of Buffalo-style pizza.

Vintage black-and-white photo of four smiling people posing on a city street in front of a restaurant sign that reads 'Santora's Pizzeria Napolitana Restaurant.' Two cars are visible in motion.